Hardware

The Cell Biology Research Unit (URBC) has the facilities for most of the methods related to cell biology, biochemistry and molecular biology. The equipment devoted to cell biology and biochemistry includes cell culture facilities, a confocal microscope, 1D-gel and 2D-gel platforms, two mass spectrometers, a radioactivity laboratory and several types of spectrophotometers, spectrofluorimeters and luminometers. Molecular biology methods available in the laboratory include PCR, real time PCR, gene transfection, plasmid amplification, and gene expression analysis by DNA microarrays.

In the field of medicinal chemistry and pharmacology the following equipment and facilities are available at the Drug Design and Discovery Center : Classical and parallel organic, synthesis equipment, Preparative LC/MS equipment, LC/MS, LC/UV analyzer, GC/FID analyzer, 1HNMR (400 MHz), 13C-NMR (400 MHz), Elemental analyzer (C, H, N, S), UV-spectrophotometer, IR-spectrophotometer, X-ray diffractometer (powder + monocrystals),
FPLC, Differencial calorimtry analysis, X-ray diffractometer, Full automated titrator, Melting point apparatus, Animal housing, Organ bath for contractions measurement, Cages equipped with particle suspension generator.

Characterisation pole has several equipments for spectroscopic analysis and nanomaterial synthesis. One can cite a linear accelerator for nuclear reactions based spectroscopy (measure of nanomaterial traces in organs, pellets, …), an ion implanter and several PVD machines for the synthesis of nanomaterials by vacuum based techniques, surface profilometry, FEG-SEM with EDX equipped with nanoparticles detection and analysis software (1 nm resolution) , SolidWorks mechanical design solutions (2D, 3D) to design animals related hardware, computational fluid dynamics programs to design suspension of nanoparticles in closed systems, …

CES main equipments : 5 potentiostats for analysis, modifications and electrochemical depositions, 1 electrochemical impedance spectroscopy (EIS), 1 scanning vibrating electrode/scanning. Kelvin probe (SKP & SVET), 1 scanning electrochemical miscroscope (SECM), 1 FT-IRRAS with modulation of polarization coupled to an IR microscope, 1 contact angle measurement, 1 ball-mill and CNTs functionalisation, 1 oven for synthesis et modification of CNTs, 1 lyophilisation instrument.